Oral Cavity Cancers –Early Detection and Outcomes

نویسندگان

  • Nirupama Moran
  • Debajit Sarma
چکیده

Background And Objectives: Oral cavity cancer is a one of the common form of malignancies in the northeastern India. This study was to analyze, treatments and outcomes of oral cancers. Materials And Methods: The study was conducted in the department of Otorhinolaryngology and head Neck Surgery, Assam Medical College and Hospital, Dibrugarh, Assam, India between February 2014 to September 2015. Results: Out of 160 newly diagnosed cases, 10 cases were selected for surgery. 30-40 years buccal mucosa and lips 32(20%), 40-50 years buccal mucosa and gums 22(13.75%) , Retro molar trigone , 50-60 years buccal mucosa and oral tongue 76(47%), 60—70 years Hard palate , retromolar trigone andfloor of mouth 22(13.75%) and 70-80 years Gums and cheek mucosa 8(5%). Out of 10 cases, 6 cases for buccal mucosa cancer wide local excision(WLE) reconstruction with pectoralis major myocutaneous(PMMC) flap and Modified radical neck dissection (MRND) type III, 2 cases for lips cancer wide local excision recontruction with deltopectoral flap,1 case cancer lateral border of tongue WLE reconstruction with submental flap with MRND TYPE I and 1 case for floor of mouth carcinoma WLE oral reconstruction with submental flap and selective neck dissection was done. Recurrence of disease was seen one patient. Conclusion: Oral Tobacco smoking, taking alcohol and betel nut are the main prevailing factor .Early detection of the oral cancer can prolongs the survival time of the patients.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pre-Cancerous Lesions in the Oral and Maxillofacial Region: A Literature Review with Special Focus on Etiopathogenesis

Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral squamous cell carcinomas (OSCCs) develop from pre-malignant lesions and conditions. Despite adv...

متن کامل

E6-Specific Detection and Typing of Human Papillomaviruses in Oral Cavity Specimens from Iranian Patients

Background: Detection and quantification of human Papillomavirus (HPV) genome in oral carcinoma play an important role in diagnosis, as well as implications for progression of disease. Methods: We evaluated tissues from 50 esopharyngeal cancers collected from different regions of Iran for HPV E6 using the two type-specific primers sets. E6 gene of HPV genotypes was amplified by specific primers...

متن کامل

A rapid, early detection of oral squamous cell carcinoma: Real time PCR based detection of tetranectin

The current study is focused on determining the mRNA expression levels of tetranectin, to detect oral squamous cell carcinoma (OSCC) and thus aiding in its classification at an early stage. RNA was isolated and cDNA synthesis was performed from the saliva samples of the patients and healthy individuals. A semiquantitative PCR based analysis was performed prior to quantitative and expression bas...

متن کامل

A rapid, early detection of oral squamous cell carcinoma: Real time PCR based detection of tetranectin

The current study is focused on determining the mRNA expression levels of tetranectin, to detect oral squamous cell carcinoma (OSCC) and thus aiding in its classification at an early stage. RNA was isolated and cDNA synthesis was performed from the saliva samples of the patients and healthy individuals. A semiquantitative PCR based analysis was performed prior to quantitative and expression bas...

متن کامل

Oral cancer screening: 5 minutes to save a life.

colleagues report the first solid evidence that periodic examination of the oral cavity can reduce mortality from oral cancer in high-risk individuals. These results come from the Kerala screening trial, a cluster randomised trial, designed to have 80% power to detect a 35% reduction in oral cancer mortality within 12 years of enrolment between the intervention and control group, through rounds...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016